Web1 May 2016 · Plaque echogenicity, total plaque area, and plaque surface irregularities have all been suggested as ultrasound markers of unstable plaques and increased stroke risk (22-25). Total plaque area has been shown to be a more sensitive and reliable measure of atherosclerotic burden than IMT and plaque ( 26 ). Web11 hours ago · Using single-cell RNA sequencing, researchers identified 12 atherosclerosis-associated cell states and found that Vcam1+ smooth muscle cell state contributed the most to the genetic heritability of coronary artery disease. A hybrid polygenic risk score (PRS) that considers cell-type-specific regulatory elements demonstrated improved …
Arteriosclerosis Radiology Reference Article Radiopaedia.org
Web26 Sep 2024 · Atherosclerosis is a condition affecting large and medium sized arteries. It involves the formation of atherosclerotic plaques within the tunica intima of these arteries. These plaques often form at places where flow of blood is more turbulent, for example at branching points of arteries. WebVascular smooth muscle cells (VSMCs) play a key role in atherogenesis and have historically been considered beneficial for plaque stability. VSMCs constitute the main cellular … protected compound interest account
Atherosclerosis - Heart and Blood Vessel Disorders - MSD Manual ...
WebFigure 1 Collagens and smooth muscle cells (SMCs) in atherosclerosis. (A) In the normal vessel wall, SMCs are in the contractile phenotype and reside in a stable ECM which is rich in types I and III collagen. (B) During atherosclerotic plaque development, SMCs transition to the synthetic phenotype, and begin to synthesize ECM, which influences cell WebAtherosclerosis is an inflammatory disease initiated by endothelial activation, in which lipoprotein, cholesterol, extracellular matrix, and various types of immune and non … Web2 2024). Atherosclerosis is the buildup of plaque inside a person's arteries, reducing the blood flow due to the lumen within the arteries becoming thinner (NIH 2024). It is a disease that can affect any artery in the body and its name depends on the artery impacted by plaque growth (NIH 2024). Coronary artery disease occurs due to plaque buildup in the arteries … protected concerted activity examples