WebIdentification of new insulin growth factor receptor-1 (IGF-1R) inhibitors via exploring ATPas kinase domain of IGF-1R through virtual screening . × Close Log In. Log in with Facebook Log in with Google. or. Email. Password ... Web1 apr. 2024 · Villanueva J, Vultur A, Lee JT, Somasundaram R, Fukunaga-Kalabis M, Cipolla AK, Wubbenhorst B, Xu X, Gimotty PA, Kee D, Santiago-Walker AE, Letrero R, …
UniProt
Web22 mrt. 2013 · The IGF-1R is a receptor tyrosine kinase which is widely expressed in many human tissues and cell types and is highly homologous to the IR. However, these … WebPicropodophyllin (PPP, AXL1717) is a IGF-1R inhibitor with IC50 of 1 nM. It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR, or of … edf6 エアレイダー 装備
National Center for Biotechnology Information
WebIGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death. … Web11 apr. 2024 · IGF-1 is widely distributed in ovarian tissue and has an antiapoptotic effect. In rats with acute and chronic POF, there were strong positive signals of apoptosis of follicles and granulosa cells in ovarian tissue, along with a significant reduction in IGF-1 expression in granulosa cells. Web7 apr. 2024 · IGF-1 can have immense muscle-boosting and fat-trimming effects, which explains why the World Anti-Doping Agency has long included the hormone on its list of prohibited substances in sports. edf6 アーマー稼ぎ放置